The Limited in Vitro Lifetime of Human Diploid Cell Strains.

Karyological Characteristics of two Human Diploid Cell Strains; WI-38 and MRC-5

"The Limited In Vitro Lifetime of Human Diploid Cell Strains" (1964), by Leonard Hayflick

Leonard Hayflick [3] in the US during the early 1960s showed that normal populations of embryonic cells divide a finite number of times. He published his results as "The Limited In Vitro Lifetime of Human Diploid Cell Strains" in 1964. Hayflick performed the experiment with WI-38 fetal lung cells, named after the Wistar Institute, in Philadelphia, Pennsylvania, where Hayflick worked. Frank MacF...

Improvement in the yield of oral poliovirus vaccine (Sabin strains) produced in human diploid cells

The Isolation and Characterization a Human Diploid Cell Strain and Its Use in Production of Measles Vaccine

Mesenchymal Stem/Stromal-Like Cells from Diploid and Triploid Human Embryonic Stem Cells Display Different Gene Expression Profiles

Background: Human ESCs-MSCs open a new insight into future cell therapy applications, due to their unique characteristics, including immunomodulatory features, proliferation, and differentiation. Methods: Herein, hESCs-MSCs were characterized by IF technique with CD105 and FIBRONECTIN as markers and FIBRONECTIN, VIMENTIN, CD10, CD105, and CD14 genes using RT-PCR technique. FACS was performed fo...